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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1995-1-26
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pubmed:abstractText |
Of 1506 black males participating in the first Abidjan semi-marathon, 123 subjects with sickle cell trait (SCT) were detected, i.e., 8.7%. Twenty-nine of these subjects with hemoglobin S (HbS) were ranked among the first 332 participants to finish the race, a percentage of 8.2. These percentages did not significantly differ from the prevalence of SCT observed in the general Ivory Coast population (12.0%). Only one subject with SCT was found among the 22 internationally-ranked athletes. The concentration of HbS found in this athlete (37.7%), his mean globular volume (87 fl), and his hemoglobin concentration (13.8 g/100 ml) suggest the coexistence of alpha-thalassemia with SCT. These results indicate that the percentage of SCT individuals participating in a semi-marathon is equal to the prevalence of SCT found in the local population. Furthermore, the general ranking of SCT individuals is comparable to that of non-SCT individuals. Nevertheless, at the level of internationally-ranked performance, no subject with SCT only, was ranked; the one ranked subject with SCT presented an associated alpha thalassemia. We thus hypothesize that SCT may be a limiting factor for high level performance in a semi-marathon and alpha-thalassemia, an enhancing factor for subjects with SCT to succeed in long distance races.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0172-4622
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
399-402
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8002118-Adolescent,
pubmed-meshheading:8002118-Adult,
pubmed-meshheading:8002118-African Continental Ancestry Group,
pubmed-meshheading:8002118-Cote d'Ivoire,
pubmed-meshheading:8002118-Erythrocyte Volume,
pubmed-meshheading:8002118-Hemoglobin, Sickle,
pubmed-meshheading:8002118-Hemoglobins,
pubmed-meshheading:8002118-Humans,
pubmed-meshheading:8002118-Male,
pubmed-meshheading:8002118-Middle Aged,
pubmed-meshheading:8002118-Physical Endurance,
pubmed-meshheading:8002118-Psychomotor Performance,
pubmed-meshheading:8002118-Running,
pubmed-meshheading:8002118-Sickle Cell Trait,
pubmed-meshheading:8002118-alpha-Thalassemia
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pubmed:year |
1994
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pubmed:articleTitle |
Sickle cell trait as a limiting factor for high-level performance in a semi-marathon.
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pubmed:affiliation |
Service d'Exploration de la Fonction Respiratoire, Hôpital Arnaud de Villeneuve, Montpellier.
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pubmed:publicationType |
Journal Article
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