Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1995-1-26
pubmed:abstractText
Of 1506 black males participating in the first Abidjan semi-marathon, 123 subjects with sickle cell trait (SCT) were detected, i.e., 8.7%. Twenty-nine of these subjects with hemoglobin S (HbS) were ranked among the first 332 participants to finish the race, a percentage of 8.2. These percentages did not significantly differ from the prevalence of SCT observed in the general Ivory Coast population (12.0%). Only one subject with SCT was found among the 22 internationally-ranked athletes. The concentration of HbS found in this athlete (37.7%), his mean globular volume (87 fl), and his hemoglobin concentration (13.8 g/100 ml) suggest the coexistence of alpha-thalassemia with SCT. These results indicate that the percentage of SCT individuals participating in a semi-marathon is equal to the prevalence of SCT found in the local population. Furthermore, the general ranking of SCT individuals is comparable to that of non-SCT individuals. Nevertheless, at the level of internationally-ranked performance, no subject with SCT only, was ranked; the one ranked subject with SCT presented an associated alpha thalassemia. We thus hypothesize that SCT may be a limiting factor for high level performance in a semi-marathon and alpha-thalassemia, an enhancing factor for subjects with SCT to succeed in long distance races.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0172-4622
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
399-402
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Sickle cell trait as a limiting factor for high-level performance in a semi-marathon.
pubmed:affiliation
Service d'Exploration de la Fonction Respiratoire, Hôpital Arnaud de Villeneuve, Montpellier.
pubmed:publicationType
Journal Article