pubmed-article:8000565 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8000565 | lifeskim:mentions | umls-concept:C0034493 | lld:lifeskim |
pubmed-article:8000565 | lifeskim:mentions | umls-concept:C2339528 | lld:lifeskim |
pubmed-article:8000565 | lifeskim:mentions | umls-concept:C0521116 | lld:lifeskim |
pubmed-article:8000565 | pubmed:issue | 9 | lld:pubmed |
pubmed-article:8000565 | pubmed:dateCreated | 1995-1-25 | lld:pubmed |
pubmed-article:8000565 | pubmed:abstractText | The voltage-gated currents of the astrocytes associated with the retinal capillaries of the rabbit retina were studied using whole-cell patch clamp recording. The resting potential of these cells was -70 +/- 4.8 mV (mean +/- SEM; n = 54), and the input resistance and cell capacitance were 558 +/- 3.6 M omega and 19.5 +/- 1.8 pF respectively. Depolarization to potentials positive to -50 mV evoked rapidly activating inward and outward currents. The inward current was transient, eliminated by substitution of choline for Na+ in the bathing solution, and reduced by 50% in the presence of 1 microM tetrodotoxin. The time-to-peak of the Na+ current was more than twice that for the Na+ current found in retinal neurons. The glial Na+ current was half-inactivated at -55 mV. A transient component of the outward K+ current was blocked by external 4-aminopyridine while a more sustained component was blocked by external tetraethylammonium. At potentials between -150 and -50 mV the membrane behaved Ohmically. Voltage-gated currents in retinal astrocytes recorded in situ appear qualitatively similar to those described for some glial cells in vitro. | lld:pubmed |
pubmed-article:8000565 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8000565 | pubmed:language | eng | lld:pubmed |
pubmed-article:8000565 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8000565 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8000565 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8000565 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8000565 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8000565 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8000565 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8000565 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8000565 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8000565 | pubmed:month | Sep | lld:pubmed |
pubmed-article:8000565 | pubmed:issn | 0953-816X | lld:pubmed |
pubmed-article:8000565 | pubmed:author | pubmed-author:ClarkB ABA | lld:pubmed |
pubmed-article:8000565 | pubmed:author | pubmed-author:MobbsPP | lld:pubmed |
pubmed-article:8000565 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8000565 | pubmed:day | 1 | lld:pubmed |
pubmed-article:8000565 | pubmed:volume | 6 | lld:pubmed |
pubmed-article:8000565 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8000565 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8000565 | pubmed:pagination | 1406-14 | lld:pubmed |
pubmed-article:8000565 | pubmed:dateRevised | 2009-9-29 | lld:pubmed |
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pubmed-article:8000565 | pubmed:year | 1994 | lld:pubmed |
pubmed-article:8000565 | pubmed:articleTitle | Voltage-gated currents in rabbit retinal astrocytes. | lld:pubmed |
pubmed-article:8000565 | pubmed:affiliation | Department of Physiology, University College London, UK. | lld:pubmed |
pubmed-article:8000565 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8000565 | pubmed:publicationType | In Vitro | lld:pubmed |
pubmed-article:8000565 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |