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pubmed-article:7993207pubmed:abstractTextWe performed a randomized controlled clinical trial to assess the safety and efficacy of a 1 microgram/h ganciclovir implant for the treatment of newly diagnosed cytomegalovirus (CMV) retinitis in patients with the acquired immunodeficiency syndrome (AIDS). Patients with previously untreated peripheral CMV retinitis were randomly assigned either to immediate treatment with the ganciclovir implant or to deferred treatment. Standardized fundus photographs were taken at 2-week intervals and analyzed in a masked fashion. The study end point was progression of retinitis based on the photographic assessment.lld:pubmed
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pubmed-article:7993207pubmed:articleTitleTreatment of cytomegalovirus retinitis with an intraocular sustained-release ganciclovir implant. A randomized controlled clinical trial.lld:pubmed
pubmed-article:7993207pubmed:affiliationNational Eye Institute, National Institutes of Health, Bethesda, Md.lld:pubmed
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