Ganciclovir

Source:http://linkedlifedata.com/resource/umls/id/C0017066

MSH: An ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.,CSP: 9-(1,3-dihydroxy-2-propoxy)methylguanine; acyclovir analog which inhibits DNA replication of CMV and therefore has efficacy against AIDS-related oculopathy.,NCI: An antiviral agent used to prevent or treat cytomegalovirus infections that may occur when the body's immune system is suppressed. In gene therapy, ganciclovir is used with an altered herpes simplex virus-1 gene to kill advanced melanoma cells and brain tumor cells.,CSP: family of acyclovir analogs with antiviral efficacy against herpes simplex and cytomegalovirus, a cause of AIDS-related blindness.,PDQ: A synthetic guanine derivative with antiviral activity. As the active metabolite of ganciclovir, ganciclovir-5-triphosphate (ganciclovir-TP) appears to inhibit viral DNA synthesis by competitive inhibition of viral DNA polymerases and incorporation int

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