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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
16
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pubmed:dateCreated |
1995-1-11
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pubmed:abstractText |
The clinical course of 16 patients with polycythemia vera (PV), treated in the period 1982 to 1993, was shown. Splenomegaly occurred in three fourths of these patients (75%), and hypertension was a major symptom. Thrombosis such as myocardial infarction and cerebral infarction was noted. Eight patients was treated with myelosuppressive agents and the 8 other patients were treated with phlebotomy. A 70-year-old male who was treated with mitobronitol (DBM) developed acute myeloblastic leukemia (AML) 11 years later. He was treated with multi-combination chemotherapy (BHAC-DMP), and entered complete remission, followed by early relapse. He became refractory to chemotherapy and died of acute pneumonia 6 months later. Median survival of 16 cases of PV was more than 10 years, and long-term treatment and care are necessary.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0385-0684
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2833-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:7993124-Adult,
pubmed-meshheading:7993124-Aged,
pubmed-meshheading:7993124-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:7993124-Female,
pubmed-meshheading:7993124-Humans,
pubmed-meshheading:7993124-Hypertension,
pubmed-meshheading:7993124-Leukemia, Myeloid, Acute,
pubmed-meshheading:7993124-Male,
pubmed-meshheading:7993124-Middle Aged,
pubmed-meshheading:7993124-Mitobronitol,
pubmed-meshheading:7993124-Nitrosourea Compounds,
pubmed-meshheading:7993124-Polycythemia Vera,
pubmed-meshheading:7993124-Prognosis
|
pubmed:year |
1994
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pubmed:articleTitle |
[A clinical study of sixteen polycythemia vera cases--acute myeloblastic leukemia in patients with polycythemia vera].
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pubmed:affiliation |
Dept. of Internal Medicine, Nagoya Ekisaikai Hospital.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
English Abstract
|