| pubmed-article:7992055 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7992055 | lifeskim:mentions | umls-concept:C0072899 | lld:lifeskim |
| pubmed-article:7992055 | lifeskim:mentions | umls-concept:C0035700 | lld:lifeskim |
| pubmed-article:7992055 | lifeskim:mentions | umls-concept:C0162782 | lld:lifeskim |
| pubmed-article:7992055 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
| pubmed-article:7992055 | lifeskim:mentions | umls-concept:C0439799 | lld:lifeskim |
| pubmed-article:7992055 | lifeskim:mentions | umls-concept:C0871161 | lld:lifeskim |
| pubmed-article:7992055 | pubmed:issue | 5191 | lld:pubmed |
| pubmed-article:7992055 | pubmed:dateCreated | 1995-1-10 | lld:pubmed |
| pubmed-article:7992055 | pubmed:abstractText | AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor channels mediate the fast component of excitatory postsynaptic currents in the central nervous system. Site-selective nuclear RNA editing controls the calcium permeability of these channels, and RNA editing at a second site is shown here to affect the kinetic aspects of these channels in rat brain. In three of the four AMPA receptor subunits (GluR-B, -C, and -D), intronic elements determine a codon switch (AGA, arginine, to GGA, glycine) in the primary transcripts in a position termed the R/G site, which immediately precedes the alternatively spliced modules "flip" and "flop." The extent of editing at this site progresses with brain development in a manner specific for subunit and splice form, and edited channels possess faster recovery rates from desensitization. | lld:pubmed |
| pubmed-article:7992055 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:7992055 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:7992055 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7992055 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:7992055 | pubmed:issn | 0036-8075 | lld:pubmed |
| pubmed-article:7992055 | pubmed:author | pubmed-author:HiguchiMM | lld:pubmed |
| pubmed-article:7992055 | pubmed:author | pubmed-author:BachAA | lld:pubmed |
| pubmed-article:7992055 | pubmed:author | pubmed-author:SeeburgP HPH | lld:pubmed |
| pubmed-article:7992055 | pubmed:author | pubmed-author:GeigerJ RJR | lld:pubmed |
| pubmed-article:7992055 | pubmed:author | pubmed-author:MelcherTT | lld:pubmed |
| pubmed-article:7992055 | pubmed:author | pubmed-author:MonyerHH | lld:pubmed |
| pubmed-article:7992055 | pubmed:author | pubmed-author:LomeliHH | lld:pubmed |
| pubmed-article:7992055 | pubmed:author | pubmed-author:HögelRR | lld:pubmed |
| pubmed-article:7992055 | pubmed:author | pubmed-author:MosbacherJJ | lld:pubmed |
| pubmed-article:7992055 | pubmed:author | pubmed-author:KunerTT | lld:pubmed |
| pubmed-article:7992055 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7992055 | pubmed:day | 9 | lld:pubmed |
| pubmed-article:7992055 | pubmed:volume | 266 | lld:pubmed |
| pubmed-article:7992055 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7992055 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7992055 | pubmed:pagination | 1709-13 | lld:pubmed |
| pubmed-article:7992055 | pubmed:dateRevised | 2007-3-19 | lld:pubmed |
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| pubmed-article:7992055 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:7992055 | pubmed:articleTitle | Control of kinetic properties of AMPA receptor channels by nuclear RNA editing. | lld:pubmed |
| pubmed-article:7992055 | pubmed:affiliation | Laboratory of Molecular Neuroendocrinology, University of Heidelberg, Germany. | lld:pubmed |
| pubmed-article:7992055 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7992055 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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