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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1995-1-10
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pubmed:abstractText |
Although renal-failure-related hyperphosphataemia can be corrected by various phosphate binders, there remains a need for safer and more efficient formulations to precipitate phosphate. This work describes both a theoretical approach and a phosphate precipitation test in order to design efficient binding calcium salts formulations. The results show that the combination of a soluble calcium salt (the gluconolactate) and a proton-consuming calcium salt (the carbonate) can precipitate phosphate effectively. Furthermore, the theoretical computations correlate well with the ability of the salt to bind phosphate in vitro.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0269-4727
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
233-8
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:7989401-Acetic Acid,
pubmed-meshheading:7989401-Acetic Acids,
pubmed-meshheading:7989401-Calcium Carbonate,
pubmed-meshheading:7989401-Calcium Gluconate,
pubmed-meshheading:7989401-Humans,
pubmed-meshheading:7989401-Hydrogen-Ion Concentration,
pubmed-meshheading:7989401-Models, Chemical,
pubmed-meshheading:7989401-Phosphates,
pubmed-meshheading:7989401-Renal Insufficiency,
pubmed-meshheading:7989401-Spectrophotometry, Atomic
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pubmed:year |
1994
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pubmed:articleTitle |
Efficient phosphate binding using a combination of gluconolactate and carbonate calcium salts.
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pubmed:affiliation |
Pharmacie Centrale des Hôpitaux de Paris, France.
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pubmed:publicationType |
Journal Article
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