Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-1-12
pubmed:abstractText
This study was undertaken to evaluate the effects of 5 months of alpha-tocopherol supplementation on physical performance during aerobic exercise training in 30 top-class cyclists. Antioxidative effects of supplementation were also studied. Plasma alpha-tocopherol concentration increased significantly in the vitamin E-supplemented group, whereas the placebo group showed a trend toward decrease. Physical performance did not improve in the alpha-tocopherol-supplemented group compared to the placebo group. Heart rates were also not significantly different. Lactate concentrations at the aerobic threshold and the anaerobic threshold were identical. Thus, there was no performance improvement in the alpha-tocopherol-supplemented group. However there was a significant reduction in CK in serum of the E-supplemented group. A trend toward decrease in GOT, GPT, and LDH was observed with alpha-tocopherol supplementation. Moreover, significantly reduced malondialdehyde serum levels were measured in the E-supplemented group. The findings indicate a protective effect of alpha-tocopherol supplementation against oxidative stress induced by strenuous exercise.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1050-1606
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
253-64
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:7987360-Adult, pubmed-meshheading:7987360-Alanine Transaminase, pubmed-meshheading:7987360-Anaerobic Threshold, pubmed-meshheading:7987360-Antioxidants, pubmed-meshheading:7987360-Aspartate Aminotransferases, pubmed-meshheading:7987360-Bicycling, pubmed-meshheading:7987360-Creatine Kinase, pubmed-meshheading:7987360-Double-Blind Method, pubmed-meshheading:7987360-Heart Rate, pubmed-meshheading:7987360-Humans, pubmed-meshheading:7987360-L-Lactate Dehydrogenase, pubmed-meshheading:7987360-Lactates, pubmed-meshheading:7987360-Male, pubmed-meshheading:7987360-Malondialdehyde, pubmed-meshheading:7987360-Oxidative Stress, pubmed-meshheading:7987360-Oxygen Consumption, pubmed-meshheading:7987360-Physical Endurance, pubmed-meshheading:7987360-Placebos, pubmed-meshheading:7987360-Psychomotor Performance, pubmed-meshheading:7987360-Stress, Physiological, pubmed-meshheading:7987360-Vitamin E
pubmed:year
1994
pubmed:articleTitle
alpha-Tocopherol supplementation in racing cyclists during extreme endurance training.
pubmed:affiliation
Institute of Forensic Medicine, University Hospital, Freiburg, Germany.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial