Linked Life Data

7986280

Source:http://linkedlifedata.com/resource/pubmed/id/7986280

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1995-1-12
pubmed:abstractText
The effect of ethyl alcohol on upper airway reflex sensitivity (UARS) has not been previously investigated in humans. Using a technique that we have previously described, intermittent breaths of low concentrations of ammonia vapour were used to measure the effect of ethyl alcohol 0.55-0.66 g/kg on UARS in ten healthy male volunteers. The depression of upper airway reflexes that occurred following ingestion of ethyl alcohol was maximum at 60 min and returned to baseline by 150 min. This dose of ethyl alcohol was insufficient to produce statistically significant depression of UARS. The blood alcohol levels achieved showed a wide range with a mean of 78.9 mg/100 ml (SEM 10.3). Individual subjects who had blood alcohol levels in excess of 100 mg/100 ml displayed much greater depression of UARS. In conclusion, 0.55-0.66 g/kg ethyl alcohol given to healthy male volunteers does not produce significant depression of UARS as measured using an ammonia stimulus technique.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0735-0414
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
425-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
The effect of ethyl alcohol on the sensitivity of upper airway reflexes.
pubmed:affiliation
Queens Medical Centre, Nottingham, U.K.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial, Research Support, Non-U.S. Gov't