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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1995-1-3
|
| pubmed:abstractText |
Incubation of rat hippocampal slices with the synthetic cannabinoid (-)-11-OH-delta 8-dimethylheptyl tetrahydrocannabinol (HU-210) (100 nM) prevented the induction of long-term potentiation of field excitatory postsynaptic potentials recorded in the CA1 region. However, in slices incubated with its non-psychoactive (+)-isomer HU-211 (100 nM), which is reported to be an NMDA receptor antagonist, high frequency stimulation evoked a long-lasting potentiation, comparable to control slices.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0014-2999
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
11
|
| pubmed:volume |
259
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
R7-8
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:7982446-Animals,
pubmed-meshheading:7982446-Cannabinoids,
pubmed-meshheading:7982446-Electric Stimulation,
pubmed-meshheading:7982446-Hippocampus,
pubmed-meshheading:7982446-Long-Term Potentiation,
pubmed-meshheading:7982446-Nerve Fibers,
pubmed-meshheading:7982446-Rats,
pubmed-meshheading:7982446-Receptors, N-Methyl-D-Aspartate,
pubmed-meshheading:7982446-Stereoisomerism,
pubmed-meshheading:7982446-Synapses,
pubmed-meshheading:7982446-Tetrahydrocannabinol
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
The action of synthetic cannabinoids on the induction of long-term potentiation in the rat hippocampal slice.
|
| pubmed:affiliation |
Department of Biomedical Sciences, Marischal College, University of Aberdeen, UK.
|
| pubmed:publicationType |
Journal Article,
In Vitro
|