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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1995-1-4
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pubmed:abstractText |
Utilizing avian, porcine and canine adrenocortical cells, we have examined the effect of bursal anti-steroidogenic peptide (BASP) on adrenocorticotropin (ACTH) and dibutyryl cyclic AMP (DB-cAMP)-stimulated corticosteroid and cAMP formation. BASP significantly (P < 0.05) suppressed corticosteroid production from adrenocortical cells derived from chickens, pigs and dogs. BASP significantly increased cAMP formation (up to 10-fold) in a dose-related manner. These findings suggest that BASP structure and activity may be conserved between chicken, porcine and canine species.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:author |
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pubmed:volume |
108
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
221-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7981983-Adrenal Cortex,
pubmed-meshheading:7981983-Adrenocorticotropic Hormone,
pubmed-meshheading:7981983-Animals,
pubmed-meshheading:7981983-Bucladesine,
pubmed-meshheading:7981983-Bursa of Fabricius,
pubmed-meshheading:7981983-Chickens,
pubmed-meshheading:7981983-Corticosterone,
pubmed-meshheading:7981983-Culture Media,
pubmed-meshheading:7981983-Cyclic AMP,
pubmed-meshheading:7981983-Dogs,
pubmed-meshheading:7981983-Dose-Response Relationship, Drug,
pubmed-meshheading:7981983-Female,
pubmed-meshheading:7981983-Male,
pubmed-meshheading:7981983-Peptides,
pubmed-meshheading:7981983-Radioimmunoassay,
pubmed-meshheading:7981983-Structure-Activity Relationship,
pubmed-meshheading:7981983-Swine
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pubmed:year |
1994
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pubmed:articleTitle |
The effect of the humoral immune system-derived bursal anti-steroidogenic peptide (BASP) on corticosteroid biosynthesis in avian, porcine and canine adrenal cortical cells.
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pubmed:affiliation |
Department of Poultry Science, Texas A & M University System, College Station 77843.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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