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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1977-4-30
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pubmed:abstractText |
The AA. study 60 cases of Parkinsonism treated with levodopa associated to G31,406 (dibenzazepnic derivative), to amantadine and to a placebo. Drug-associations: 1) L-dopa + G 31.406, of anticataleptic effect, probably because of its anticholinergic activity and adrenergic central and/or dopaminergic stimulating action; 2) L-Dopa + chl. amantadine; 3) L-dopa + placebo. The patients were previously under exclusive use of L-dopa. The assay verifies: a) if there is any benefit with these associations and in what proportions; b) incidence and intensity of side effects; c) comparative study. The assay also intends to evaluate the effect of the G 31.406 on the depression which usually occur in Parkinsonians.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0028-3851
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
17
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
285-92
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:798128-Amantadine,
pubmed-meshheading:798128-Clinical Trials as Topic,
pubmed-meshheading:798128-Depression,
pubmed-meshheading:798128-Dibenzazepines,
pubmed-meshheading:798128-Drug Evaluation,
pubmed-meshheading:798128-Drug Therapy, Combination,
pubmed-meshheading:798128-Humans,
pubmed-meshheading:798128-Levodopa,
pubmed-meshheading:798128-Parkinson Disease,
pubmed-meshheading:798128-Placebos
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pubmed:year |
1976
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pubmed:articleTitle |
The L-dopa sparing effect of G 31,406 in the treatment of parkinson's disease.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Controlled Clinical Trial
|