Linked Life Data

7978374

Source:http://linkedlifedata.com/resource/pubmed/id/7978374

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1994-12-7
pubmed:abstractText
Fluorescence resonance energy transfer (FRET) was used to study the changes which human sperm chromatin went through after various physical and chemical treatments. This technique showed a dilatation of the spatial relationship among chromatin liner arrays, with UV and DNAse among the treatments that gave rise to the highest increase. FRET image analysis showed that the chromatin linear arrays after treatment reach a spatial disarrangement similar to that brought about by sperm decondensation. Comparison of these results with the ability of human treated sperm to form pronuclei after microinjection into hamster eggs, suggests that the highly condensed spatial organization of sperm chromatin arrays may not be a necessary prerequisite for pronucleus formation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0303-4569
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
225-30
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
Fluorescence energy transfer shows that various physical and chemical treatments of human sperm induce unpacking of chromatin.
pubmed:affiliation
Dipartimento di Biologia Animale, Università di Pavia, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't