Linked Life Data

7977745

Source:http://linkedlifedata.com/resource/pubmed/id/7977745

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5 Pt 1
pubmed:dateCreated
1994-12-7
pubmed:abstractText
We describe the use of magnetic stimulation of the human motor cortex and the extracranial vagus nerve in the neck to study human esophageal electromyographic (EMG) responses. Diffuse cortical stimulation produced both an early and a late EMG response in the proximal esophagus with latencies of 10.9 +/- 0.5 and 43.4 +/- 4.3 ms, respectively. Increasing the stimulation intensity increased the amplitude and duration, but reduced the latency, of the early response (P < 0.01), whereas the late response remained unchanged. The early response, but not the late response, was facilitated when cortical stimulation was performed during valsalva maneuver. Maximal early response amplitudes were obtained by focal stimulation of either hemisphere 4-8 cm lateral to the vertex. Stimulation of the neck over the extracranial vagus nerve at the angle of the jaw also produced an early and a late EMG response in the proximal esophagus with latencies of 4.3 +/- 0.4 and 56.8 +/- 14.5 ms, respectively. Early responses were also recorded in the midesophagus and distal esophagus from either cortical or vagal stimulation, but amplitudes were smaller and rise times were longer, suggesting passive "volume conduction" from the proximal esophagus. Comparison of laryngeal, pharyngeal, and esophageal early EMG responses showed similar amplitudes and rise times, suggesting that the action potentials were generated locally at each site and that true esophageal responses were being detected.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0002-9513
pubmed:author
pubmed:issnType
Print
pubmed:volume
267
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
G827-35
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Esophageal myoelectric responses to magnetic stimulation of the human cortex and the extracranial vagus nerve.
pubmed:affiliation
Department of Gastroenterology, Hope Hospital, University of Manchester, United Kingdom.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't