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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1994-12-19
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pubmed:abstractText |
The efficacy of an anthrax vaccine licensed for human use, MDPH-PA, was tested in guinea-pigs intramuscularly challenged with 10, 100 or 1000 LD50 of spores from two virulent strains of Bacillus anthracis, Vollum 1B and Ames. As demonstrated in other investigations, immunization with MDPH-PA provided better protection against challenge with the Vollum 1B strain than with the Ames strain, although vaccine efficacy against the Ames strain was better than previously reported. Enzyme-linked immunosorbent assay of serum antibody titres to B. anthracis protective antigen showed that there was no significant correlation between survival and antibody titres.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
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pubmed:issn |
0264-410X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
872-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7975827-Animals,
pubmed-meshheading:7975827-Antibodies, Bacterial,
pubmed-meshheading:7975827-Bacillus anthracis,
pubmed-meshheading:7975827-Bacterial Vaccines,
pubmed-meshheading:7975827-Female,
pubmed-meshheading:7975827-Guinea Pigs,
pubmed-meshheading:7975827-Humans,
pubmed-meshheading:7975827-Immunization,
pubmed-meshheading:7975827-Spores, Bacterial
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pubmed:year |
1994
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pubmed:articleTitle |
Efficacy of a standard human anthrax vaccine against Bacillus anthracis spore challenge in guinea-pigs.
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pubmed:affiliation |
Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702-5011.
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pubmed:publicationType |
Journal Article
|