Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1994-12-2
|
pubmed:abstractText |
42 women were randomized to receive either placebo or fluoxetine at 20 mgs per day. Inter and intra group differences in clinical variables were evaluated after 3 and 6 weeks of treatment. Except for self rated anxiety which improved in the placebo treated group at 3 weeks, no differences between groups were noted. For those receiving fluoxetine both AIMS Anxiety (4.0 baseline vs. 3.3, p = 0.04) and Depression scores (2.6 baseline vs. 1.9, p = 0.03) improved at 3 weeks; however, improvement in the Beck Depression Scale did not reach significance (11.8 vs. 9.4, p = 0.34). At 6 weeks, both AIMS Depression (2.6 at baseline and 1.5 at 6 weeks, p = 0.03) and Beck Depression Scales (11.8 at baseline vs. 8.3 at 6 weeks, p = 0.04) showed improvement, as did sleep quality (9.6 vs. 7.6, p = 0.03). But no other variable had a significant change from baseline at either the 3 or 6 week point. Our data do not suggest that fluoxetine improves the signs and symptoms of fibromyalgia.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0300-9742
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
23
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
255-9
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:7973479-Adult,
pubmed-meshheading:7973479-Aged,
pubmed-meshheading:7973479-Anxiety,
pubmed-meshheading:7973479-Depression,
pubmed-meshheading:7973479-Double-Blind Method,
pubmed-meshheading:7973479-Female,
pubmed-meshheading:7973479-Fibromyalgia,
pubmed-meshheading:7973479-Fluoxetine,
pubmed-meshheading:7973479-Humans,
pubmed-meshheading:7973479-Middle Aged,
pubmed-meshheading:7973479-Pain Measurement,
pubmed-meshheading:7973479-Psychiatric Status Rating Scales
|
pubmed:year |
1994
|
pubmed:articleTitle |
A double-blind placebo controlled trial of fluoxetine in fibromyalgia.
|
pubmed:affiliation |
Arthritis Research Center, St. Francis Research Institute, Wichita, KS 67214.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|