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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8
|
| pubmed:dateCreated |
1994-12-1
|
| pubmed:abstractText |
Rate adaptive ventricular pacemakers using central venous oxygen saturation (O2Sat) to control the pacing rate have been implanted in 14 patients (mean age 71 years), with a mean follow-up period of 44 months (range 2-63 months). In eight patients the pacemakers were replaced due to signs of battery depletion after an implant duration of 39-58 months. During bicycle exercise testing the O2Sat decreased on average from 61% +/- 4% at rest to 36% +/- 4% (P < 0.0001) at peak exercise, and the maximum pacing rate was 122 +/- 5 beats/min. The time delay until the O2Sat had dropped 10%, 65%, and 90% of the total reduction during exercise was 4.8 +/- 0.9 seconds, 39.8 +/- 3.8 seconds, and 71.3 +/- 7.5 seconds, respectively. The O2Sat decreased 9.4% +/- 2% (P < 0.005) from resting supine to resting sitting. Oxygen breathing increased the telemetered O2Sat from the pacemaker by 8.4% +/- 1% (P < 0.001). During follow-up the O2Sats were relatively stable in 50% of the patients, but demonstrated significant fluctuations in the others. At 1-year invasive follow-up O2Sat measured by the pacemaker decreased 22% +/- 2%, and in blood samples from the right ventricle 22% +/- 2% from rest to 3 minutes exercise at 25 watts. There was a significant correlation between O2Sat measured by the pacemaker and in blood samples from right ventricle (n = 105; r = 0.73; P < 0.001). In two patients the O2Sat dropped significantly during pneumonia. In another patient episodes of angina pectoris was associated with low O2Sat and a concomitant fast pacing rate.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0147-8389
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
17
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1355-72
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:7971397-Aged,
pubmed-meshheading:7971397-Aged, 80 and over,
pubmed-meshheading:7971397-Angina Pectoris,
pubmed-meshheading:7971397-Cardiac Output,
pubmed-meshheading:7971397-Cardiac Pacing, Artificial,
pubmed-meshheading:7971397-Coronary Disease,
pubmed-meshheading:7971397-Equipment Design,
pubmed-meshheading:7971397-Equipment Failure,
pubmed-meshheading:7971397-Exercise Test,
pubmed-meshheading:7971397-Female,
pubmed-meshheading:7971397-Follow-Up Studies,
pubmed-meshheading:7971397-Heart Catheterization,
pubmed-meshheading:7971397-Heart Rate,
pubmed-meshheading:7971397-Humans,
pubmed-meshheading:7971397-Male,
pubmed-meshheading:7971397-Middle Aged,
pubmed-meshheading:7971397-Oximetry,
pubmed-meshheading:7971397-Oxygen,
pubmed-meshheading:7971397-Oxygen Consumption,
pubmed-meshheading:7971397-Pacemaker, Artificial,
pubmed-meshheading:7971397-Posture,
pubmed-meshheading:7971397-Rest,
pubmed-meshheading:7971397-Telemetry
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Long-term clinical performance of a central venous oxygen saturation sensor for rate adaptive cardiac pacing.
|
| pubmed:affiliation |
Medical Department, University of Bergen, Haukeland Hospital, Norway.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|