Linked Life Data

7970234

Source:http://linkedlifedata.com/resource/pubmed/id/7970234

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-12-29
pubmed:abstractText
Genotypes of apolipoprotein E (ApoE) were determined by polymerase-chain reaction (PCR) amplification and restriction-sizing of brain DNA from 39 cases of Lewy body dementia (LBD), 68 senile Alzheimer's disease (AD) patients and 47 neuropathologically validated non-demented controls. There was a 3-fold increase in the epsilon 4 allele frequency in both LBD and AD groups compared with controls. These results indicate that LBD and AD share the epsilon 4 allele of ApoE as a major risk factor for the development of disease and suggest a similarity in disease aetiology.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
18
pubmed:volume
176
pubmed:geneSymbol
APOE
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
45-6
pubmed:dateRevised
2010-8-25
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Apolipoprotein E epsilon 4 allele frequency in patients with Lewy body dementia, Alzheimer's disease and age-matched controls.
pubmed:affiliation
MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Controlled Clinical Trial, Research Support, Non-U.S. Gov't