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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1994-12-16
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pubmed:abstractText |
Peripheral blood mononuclear cells collected from 13 patients with chronic fatigue syndrome and 13 healthy controls were analyzed for the presence of human herpesvirus 6 (HHV-6) DNA by variant-specific polymerase chain reaction and dot blot hybridization. HHV-6 DNA was detected in 7 of 13 (53%) patients, and of those 7 patients, 4 were positive for HHV-6 variant A DNA and 3 were for variant B. No HHV-6 DNA was detected in the controls. Serum antibody titers to the late antigen and antibody prevalence to the early antigen of HHV-6 were significantly higher in the patient group. These results suggest active replication of HHV-6 in patients with chronic fatigue syndrome.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0385-5600
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
587-90
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7968694-Antibodies, Viral,
pubmed-meshheading:7968694-Base Sequence,
pubmed-meshheading:7968694-DNA, Viral,
pubmed-meshheading:7968694-Fatigue Syndrome, Chronic,
pubmed-meshheading:7968694-Herpesvirus 6, Human,
pubmed-meshheading:7968694-Humans,
pubmed-meshheading:7968694-Leukocytes, Mononuclear,
pubmed-meshheading:7968694-Molecular Sequence Data,
pubmed-meshheading:7968694-Nucleic Acid Hybridization,
pubmed-meshheading:7968694-Polymerase Chain Reaction,
pubmed-meshheading:7968694-Virus Replication
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pubmed:year |
1994
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pubmed:articleTitle |
Prevalence of human herpesvirus 6 variants A and B in patients with chronic fatigue syndrome.
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pubmed:affiliation |
Department of Virology, Osaka University Medical School, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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