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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6 Pt 1
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pubmed:dateCreated |
1994-12-12
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pubmed:abstractText |
Angiomyolipomas were found in 42 kidneys in 23 female and 8 male patients at our medical center. Angiomyolipoma was diagnosed by computerized tomography (CT) alone in 55% of the cases, and by a combination of ultrasound and CT in 36%. Nine of 11 patients with bilateral angiomyolipoma had associated tuberous sclerosis. Treatment consisted of observation in 22 patients, selective arterial embolization in 6, partial nephrectomy in 6 and nephrectomy in 8. A total of 17 patients who were observed had tumors smaller than 4 cm. and 4 h had angiomyolipoma of 4 to 10 cm. With a mean followup of 3.8 years, no observation patient had subsequent renal hemorrhage and only 1 (tumor larger than 10 cm.) had radiographic progression. Despite progression, the latter patient remained asymptomatic for 18 years. Selective arterial embolization (3 tumors 4 to 10 cm. and 3 larger than 10 cm.) resulted in preservation of renal function at a mean of 1 year. All patients treated with partial nephrectomy (6 tumors 4 to 10 cm.) maintained stable renal function without recurrence during a mean 4.7-year followup. Similarly, all individuals who underwent nephrectomy (4 tumors smaller than 4 cm., 3 tumors 4 to 10 cm. and 1 tumor larger than 10 cm.) have stable renal function. We recommend renal conservation for patients with renal angiomyolipoma using a strategy of observation for small asymptomatic tumors, partial nephrectomy for moderate size tumors and selective arterial embolization of large tumors not amenable to partial nephrectomy.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0022-5347
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
152
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1988-91
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7966657-Adolescent,
pubmed-meshheading:7966657-Adult,
pubmed-meshheading:7966657-Aged,
pubmed-meshheading:7966657-Angiomyolipoma,
pubmed-meshheading:7966657-Child,
pubmed-meshheading:7966657-Child, Preschool,
pubmed-meshheading:7966657-Embolization, Therapeutic,
pubmed-meshheading:7966657-Female,
pubmed-meshheading:7966657-Follow-Up Studies,
pubmed-meshheading:7966657-Humans,
pubmed-meshheading:7966657-Infant,
pubmed-meshheading:7966657-Kidney Neoplasms,
pubmed-meshheading:7966657-Male,
pubmed-meshheading:7966657-Middle Aged,
pubmed-meshheading:7966657-Nephrectomy,
pubmed-meshheading:7966657-Treatment Outcome
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pubmed:year |
1994
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pubmed:articleTitle |
Outcome analysis of 42 cases of renal angiomyolipoma.
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pubmed:affiliation |
Department of Surgery, University of Michigan Medical Center, Ann Arbor.
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pubmed:publicationType |
Journal Article,
Clinical Trial
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