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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1977-3-31
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pubmed:abstractText |
Escherichia coli K12 cannot grow on D-lyxose, but a mutant was isolated which can utilize D-lyxose as sole source of carbon and energy for growth. D-Lyxose is transported into the bacteria by the D-xylose permease. The mutant constitutively synthesizes a new isomerase which is not inducible in the parent strain under any of the conditions tested. This enzyme, whose native substrate appears to be D-mannose, fortuitously converts D-lyxose into D-xylulose. Its structural gene is located at around 85 min on the E. coli genetic map, away from other known isomerase genes. D-Xylulose is subsequently catabolized by the enzymes of the normal D-xylose metabolic pathway. D-Mannose isomerase was partially purified and some of its properties were examined.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Carbohydrate Epimerases,
http://linkedlifedata.com/resource/pubmed/chemical/Fructose,
http://linkedlifedata.com/resource/pubmed/chemical/Mannose,
http://linkedlifedata.com/resource/pubmed/chemical/Pentoses,
http://linkedlifedata.com/resource/pubmed/chemical/Xylose,
http://linkedlifedata.com/resource/pubmed/chemical/Xylulose
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0022-1287
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
97
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
257-65
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:796410-Carbohydrate Epimerases,
pubmed-meshheading:796410-Escherichia coli,
pubmed-meshheading:796410-Fructose,
pubmed-meshheading:796410-Genes,
pubmed-meshheading:796410-Mannose,
pubmed-meshheading:796410-Mutation,
pubmed-meshheading:796410-Pentoses,
pubmed-meshheading:796410-Stereoisomerism,
pubmed-meshheading:796410-Xylose,
pubmed-meshheading:796410-Xylulose
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pubmed:year |
1976
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pubmed:articleTitle |
Growth on D-lyxose of a mutant strain of Escherichia coli K12 using a novel isomerase and enzymes related to D-xylase metabolism.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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