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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1994-12-28
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pubmed:abstractText |
Twenty symptomatic patients without erosive esophagitis underwent 24-h esophageal pH monitoring after failing standard medical antireflux treatment. Sixty-five percent had abnormal esophageal acid exposure, and the majority of these improved on proton pump inhibitor therapy. However, 35% had a normal 24-h pH test. One patient had coronary artery disease, one had diffuse esophageal spasm, and two had a negative work-up and no improvement with omeprazole. Consequently, we suggest that patients like these have an omeprazole trial. If symptoms persist, 24-h esophageal pH monitoring can appropriately define more rational management. Patients with abnormal esophageal acid exposure will require more aggressive acid-control therapy, whereas those with normal esophageal acid exposure will need further work-up to assess the cause of their symptoms.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0192-0790
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
97-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7963375-Adult,
pubmed-meshheading:7963375-Aged,
pubmed-meshheading:7963375-Aged, 80 and over,
pubmed-meshheading:7963375-Anti-Ulcer Agents,
pubmed-meshheading:7963375-Esophagitis,
pubmed-meshheading:7963375-Esophagus,
pubmed-meshheading:7963375-Female,
pubmed-meshheading:7963375-Gastroesophageal Reflux,
pubmed-meshheading:7963375-Humans,
pubmed-meshheading:7963375-Hydrogen-Ion Concentration,
pubmed-meshheading:7963375-Male,
pubmed-meshheading:7963375-Middle Aged,
pubmed-meshheading:7963375-Monitoring, Ambulatory,
pubmed-meshheading:7963375-Omeprazole,
pubmed-meshheading:7963375-Prospective Studies,
pubmed-meshheading:7963375-Proton Pumps,
pubmed-meshheading:7963375-Treatment Failure
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pubmed:year |
1994
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pubmed:articleTitle |
24-hour pH monitoring in symptomatic patients without erosive esophagitis who did not respond to antireflux treatment.
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pubmed:affiliation |
University of Arizona Health Sciences Center, Tucson.
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pubmed:publicationType |
Journal Article
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