|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0012634,
umls-concept:C0022566,
umls-concept:C0022595,
umls-concept:C0026187,
umls-concept:C0184511,
umls-concept:C0439849,
umls-concept:C0442027,
umls-concept:C0445223,
umls-concept:C0521009,
umls-concept:C1314939,
umls-concept:C1521761,
umls-concept:C1552599,
umls-concept:C1704787,
umls-concept:C2362652
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
1994-12-6
|
|
pubmed:abstractText |
Three cases of keratosis follicularis squamosa (Dohi) and one case of papillomatose confluente et reticulee were successfully treated with oral minocycline (50-100 mg/day). The clinical effect first appeared at 2 weeks after the initiation of therapy and no recurrence was observed for more than 3 months without minocycline. Gram positive cocci were demonstrated inside the hair follicle and horny layers in all 4 case. Minocycline might modulate abberant keratinization through its bactericidal effects in these keratinizing disorders.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0385-2407
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
21
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
604-8
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
pubmed-meshheading:7962961-Administration, Oral,
pubmed-meshheading:7962961-Adolescent,
pubmed-meshheading:7962961-Adult,
pubmed-meshheading:7962961-Bacteria,
pubmed-meshheading:7962961-Child,
pubmed-meshheading:7962961-Darier Disease,
pubmed-meshheading:7962961-Female,
pubmed-meshheading:7962961-Humans,
pubmed-meshheading:7962961-Male,
pubmed-meshheading:7962961-Minocycline,
pubmed-meshheading:7962961-Skin
|
|
pubmed:year |
1994
|
|
pubmed:articleTitle |
Oral minocycline improved keratosis follicularis squamosa (Dohi) and related disorder: bacterial factors are possibly involved in abberant keratinization.
|
|
pubmed:affiliation |
Department of Dermatology, Tokyo Medical and Dental University School of Medicine, Japan.
|
|
pubmed:publicationType |
Journal Article,
Case Reports
|
