Linked Life Data

7957141

Source:http://linkedlifedata.com/resource/pubmed/id/7957141

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1994-11-25
pubmed:abstractText
Endocrine regulation of hormones and electrolytes during 37.5 h of -6 degrees head down tilt (HDT) was studied in 13 men. The acute effects of simulated weightlessness are today well documented, but no study has been made concerning the hormone changes between 12 h and 2 days of HDT. Plasma volume showed a maximal increase of 9.23 (SEM 1.97)% after 6.5 h (P < 0.01) and had returned to prestudy levels after 13.5 h of HDT. From 1.5 h to 4 h of HDT, C-terminus and N-terminus atrial natriuretic peptide (ANP) concentrations in plasma were increased by about 50% (P < 0.01) and thereafter declined to pre-HDT levels. Plasma renin activity (PRA) was decreased by 47% (P < 0.05) after 4 h of HDT; PRA increased after 23.5 h to 60%; noradrenaline concentration decreased immediately and remained low up to 37.5 h. Diuresis and natriuresis were evident during the 1st day of HDT, resulting in a marked increase in the urinary Na+. These results showed that the initial hormone (ANP, PRA) changes during HDT did not last more than 13.5 h and that after 24 h a new state would seem to have been established to adapt the body to hypovolaemia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0301-5548
pubmed:author
pubmed:issnType
Print
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
497-503
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Hormone changes induced by 37.5-h head-down tilt (-6 degrees) in humans.
pubmed:affiliation
Laboratoire de Physiologie de l'Environnement, Faculté de Médecine Lyon Grange-Blanche, France.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't