rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
11
|
pubmed:dateCreated |
1977-3-15
|
pubmed:abstractText |
A double-blind cross-over study was performed on 12 men sith stable angina pectoris in order to determine the effect of antilipolytic treatment on exercise tolerance and exercise-induced electrocardiographic changes. The men were exercised to the onset of anginal pain using a reproducible and standardized ergometric load. A nicotinic acid analogue was used to reduce plasma free fatty acids and free glycerol before and during exercise testing and to eliminate their post-exercise rise. This was associated with significant reduction of exercise-induced ST segment depression (p less than 0-005), though there was no significant difference in the duration of exercise before the oneset of pain. A change in the prportions of lipid and carbohydrate for oxidation by the ischaemic myocardium, making relatively more glucose available, is a likely explanation.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0007-0769
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
38
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1204-8
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:795443-Aged,
pubmed-meshheading:795443-Angina Pectoris,
pubmed-meshheading:795443-Blood Pressure,
pubmed-meshheading:795443-Clinical Trials as Topic,
pubmed-meshheading:795443-Exercise Test,
pubmed-meshheading:795443-Fatty Acids, Nonesterified,
pubmed-meshheading:795443-Glycerol,
pubmed-meshheading:795443-Heart Rate,
pubmed-meshheading:795443-Humans,
pubmed-meshheading:795443-Hypolipidemic Agents,
pubmed-meshheading:795443-Male,
pubmed-meshheading:795443-Middle Aged,
pubmed-meshheading:795443-Nicotinic Acids,
pubmed-meshheading:795443-Placebos
|
pubmed:year |
1976
|
pubmed:articleTitle |
Antilipolytic therapy in angina pectoris. Reduction of exercise-induced ST segment depression.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial
|