Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1994-12-2
pubmed:abstractText
The nef genes of HIV and SIV are dispensable in vitro, but are essential for viral spread and disease progression in vivo. Nef-induced down-regulation of CD4, the viral receptor, may be the key to this requirement.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0960-9822
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
4
pubmed:geneSymbol
lck, nef
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
618-20
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:7953537-Animals, pubmed-meshheading:7953537-Antigens, CD4, pubmed-meshheading:7953537-CD4-Positive T-Lymphocytes, pubmed-meshheading:7953537-Cells, Cultured, pubmed-meshheading:7953537-Down-Regulation, pubmed-meshheading:7953537-Gene Products, nef, pubmed-meshheading:7953537-Genes, nef, pubmed-meshheading:7953537-HIV, pubmed-meshheading:7953537-Haplorhini, pubmed-meshheading:7953537-Humans, pubmed-meshheading:7953537-Lymphocyte Specific Protein Tyrosine Kinase p56(lck), pubmed-meshheading:7953537-Mice, pubmed-meshheading:7953537-Mice, SCID, pubmed-meshheading:7953537-Mice, Transgenic, pubmed-meshheading:7953537-Proto-Oncogene Proteins, pubmed-meshheading:7953537-Simian immunodeficiency virus, pubmed-meshheading:7953537-Virus Replication, pubmed-meshheading:7953537-nef Gene Products, Human Immunodeficiency Virus
pubmed:year
1994
pubmed:articleTitle
Immunodeficiency viruses. Not enough sans Nef.
pubmed:affiliation
Howard Hughes Medical Institute, Department of Microbiology and Immunology, University of California, San Francisco 94143-0414.
pubmed:publicationType
Journal Article, Review