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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1994-12-2
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pubmed:abstractText |
Sarcoplasmic reticulum (SR) vesicles with (1000 folds) or without transmembrane Ca2+ gradient have been prepared. Different fluorescence probes (DPH, TMA-DPH and n-AS), were used to determine the effect of transmembrane Ca2+ gradient on the lipid fluidity both in outer and inner layer of Ca(2+)-ATPase-containing SR vesicles. The results showed that transmembrane Ca2+ gradient could significantly decrease the fluidity of the inner layer of SR membrane, while no obvious change was monitored in the outer layer. This may be deduced that Ca(2+)-ATPase might be modulated mainly by the transmembrane Ca2+ gradient-mediated alteration of physical state of phospholipid in the inner layer of SR membrane.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium-Transporting ATPases,
http://linkedlifedata.com/resource/pubmed/chemical/Fluorescent Dyes,
http://linkedlifedata.com/resource/pubmed/chemical/Lipid Bilayers,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipids
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1039-9712
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
597-605
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:7951077-Animals,
pubmed-meshheading:7951077-Calcium,
pubmed-meshheading:7951077-Calcium-Transporting ATPases,
pubmed-meshheading:7951077-Cell Membrane,
pubmed-meshheading:7951077-Fluorescent Dyes,
pubmed-meshheading:7951077-Intracellular Membranes,
pubmed-meshheading:7951077-Lipid Bilayers,
pubmed-meshheading:7951077-Membrane Fluidity,
pubmed-meshheading:7951077-Phospholipids,
pubmed-meshheading:7951077-Rabbits,
pubmed-meshheading:7951077-Sarcoplasmic Reticulum
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pubmed:year |
1994
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pubmed:articleTitle |
Transmembrane Ca2+ gradient-mediated change of fluidity in the inner layer of phospholipids modulates Ca(2+)-ATPase of sarcoplasmic reticulum.
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pubmed:affiliation |
National Laboratory of Biomacromolecules, Academia Sinica, Beijing, China.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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