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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1977-2-26
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pubmed:abstractText |
The findings are reported of a controlled clinical trial comparing in 66 rheumatoid arthritis patients 0 g (placebo), and 0.50 g a day and 1 g a day of penicillamine. Each of these groups has been subdivided into two, one part receiving 5 mg a day of zinc metal supplement, the other a placebo. The trial was planned to be double-blind, and for each patient to take part for 4 months. The results prove the effectiveness of penicillamine in rheumatoid arthritis. 0.50 g a day has the same effect as 1 g a day but gives less side effects. Zinc supplement inhibits the clinical effects of penicillamine but does not prevent the side effects.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-9742
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
241-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:795022-Arthritis, Rheumatoid,
pubmed-meshheading:795022-Clinical Trials as Topic,
pubmed-meshheading:795022-Drug Evaluation,
pubmed-meshheading:795022-Drug Therapy, Combination,
pubmed-meshheading:795022-Female,
pubmed-meshheading:795022-Humans,
pubmed-meshheading:795022-Leukocyte Count,
pubmed-meshheading:795022-Male,
pubmed-meshheading:795022-Middle Aged,
pubmed-meshheading:795022-Penicillamine,
pubmed-meshheading:795022-Placebos,
pubmed-meshheading:795022-Zinc
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pubmed:year |
1976
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pubmed:articleTitle |
Controlled trial of D-penicillamine in rheumatoid arthritis. Dose effect and the role of zinc.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Controlled Clinical Trial
|