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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
1994-12-15
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pubmed:abstractText |
Matrix-assisted laser desorption/ionization using a 3-hydroxypicolinic acid matrix from an active Nafion substrate has been used for detection of restriction enzyme-digested double-stranded plasmid DNA using time-of-flight mass spectrometry. DNA strands of up to 267 base pairs were detected with minimal sample purification, although only as species corresponding to single-stranded DNA.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0951-4198
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
687-91
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7949333-Base Sequence,
pubmed-meshheading:7949333-DNA,
pubmed-meshheading:7949333-DNA Restriction Enzymes,
pubmed-meshheading:7949333-Fluorocarbon Polymers,
pubmed-meshheading:7949333-Humans,
pubmed-meshheading:7949333-Lasers,
pubmed-meshheading:7949333-Mass Spectrometry,
pubmed-meshheading:7949333-Molecular Sequence Data,
pubmed-meshheading:7949333-Picolinic Acids,
pubmed-meshheading:7949333-Plasmids,
pubmed-meshheading:7949333-Polymerase Chain Reaction
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pubmed:year |
1994
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pubmed:articleTitle |
Matrix-assisted laser desorption/ionization mass spectrometry of restriction enzyme-digested plasmid DNA using an active Nafion substrate.
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pubmed:affiliation |
Department of Chemistry, University of Michigan, Ann Arbor 48109.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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