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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1994-12-2
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pubmed:abstractText |
20 alpha-hydroxysteroid dehydrogenase (20 alpha-HSD) activities in 57 neoplastic tissues surgically removed from dogs were measured. Forty-eight of 57 tumor samples were shown to possess 20 alpha-HSD activity. These tissues were histopathologically classified into 22 benign and 26 malignant tumors. Among these tumors, mixed tumor types demonstrated the higher 20 alpha-HSD activity than epithelial and non-epithelial types, and malignant tumors of each tissue type showed slightly but not significantly higher 20 alpha-HSD activities comparing with the corresponding benign ones. Comparing with the activity of normal tissues examined, the corresponding tumor tissues showed significantly higher 20 alpha-HSD activities. Thus, 20 alpha-HSD activity was found in neoplastic tissues at a considerable high rate and the activity seemed to be higher in pathologically malignant tumors.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0916-7250
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
581-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7948398-20-Hydroxysteroid Dehydrogenases,
pubmed-meshheading:7948398-20-alpha-Hydroxysteroid Dehydrogenase,
pubmed-meshheading:7948398-Animals,
pubmed-meshheading:7948398-Anus Neoplasms,
pubmed-meshheading:7948398-Dog Diseases,
pubmed-meshheading:7948398-Dogs,
pubmed-meshheading:7948398-Female,
pubmed-meshheading:7948398-Liver Neoplasms,
pubmed-meshheading:7948398-Male,
pubmed-meshheading:7948398-Mammary Neoplasms, Animal,
pubmed-meshheading:7948398-Neoplasms,
pubmed-meshheading:7948398-Ovarian Neoplasms,
pubmed-meshheading:7948398-Skin Neoplasms,
pubmed-meshheading:7948398-Testicular Neoplasms
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pubmed:year |
1994
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pubmed:articleTitle |
20 alpha-hydroxysteroid dehydrogenase activity in canine spontaneous neoplasms.
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pubmed:affiliation |
Department of Veterinary Surgery, University of Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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