Linked Life Data

7947344

Source:http://linkedlifedata.com/resource/pubmed/id/7947344

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1994-12-2
pubmed:abstractText
The present study was directed towards identification of proteins synthesized and secreted by the cervix, uterus and oviduct of immature hamsters and by the uterus of ovariectomized adult hamsters. Hamsters were treated with estradiol, progesterone or testosterone for 3 consecutive days after which the tissues were incubated in vitro and [35S]methionine labelled proteins were analyzed by sodium dodecyl sulfate polyacrylamide gel electrophoresis. The results demonstrate a great degree of similarity between the proteins synthesized and secreted by the cervix, uterus and oviduct of hamsters. Treatment of hamsters with estradiol consistently increased the synthesis of a 60 kDa protein in the cervix, uterus and oviduct. Further, estradiol also consistently suppressed the synthesis of a 14, 30 and 72 kDa protein in the uterus but not in the cervix and oviduct. In the cervix, in addition to the 60 kDa protein estradiol also induced the synthesis of two other proteins (a 38 and 56 kDa protein). Testosterone and progesterone did not induce or suppress the synthesis of the secretory proteins in the hamster cervix, uterus and oviduct. In hamster the 60 kDa protein could serve as a marker of gene expression following hormone action.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0960-0760
pubmed:author
pubmed:issnType
Print
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
107-14
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Secretory proteins of the hamster cervix, uterus and oviduct: the effects of estradiol, progesterone and testosterone on the proteins secreted into the medium.
pubmed:affiliation
Centre for Cellular and Molecular Biology, Hyderabad, India.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't