Linked Life Data

7947000

Source:http://linkedlifedata.com/resource/pubmed/id/7947000

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1994-12-14
pubmed:abstractText
The presence and number of breast cancer micrometastases in the bone marrow at the time of diagnosis or initial treatment appear to predict early distant relapse. Immunologic techniques to detect such bone micrometastases, in combination with traditional prognostic variables, such as axillary lymph node status and tumor diameter, may allow for the identification of patients at high risk of systemic disease, who may benefit from adjuvant systemic chemotherapy. Immunofluorescent and immunochemical monoclonal antibody techniques have similar sensitivity in the detection of cancer cells in bone marrow. Future research is needed to develop more specific monoclonal antibodies and to determine the characteristics of the primary tumor that correlate with bone marrow micrometastasis, as well as the characteristics of micrometastases that correlate with recurrence.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0890-9091
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
25-31; discussion 35-6, 39-42
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Detection and management of bone marrow micrometastases in breast cancer.
pubmed:affiliation
Department of Surgery, New York Hospital-Cornell University Medical Center; Strang Cancer Prevention Center, New York.
pubmed:publicationType
Journal Article, Review