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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1994-12-14
|
pubmed:abstractText |
A pulse of light is capable of inducing the circadian phase-dependent gene expression in neurons. The phase or amplitude of the circadian rhythms can be modulated by critically timed exposures to light. A significant heritability for the light-induced responses has been observed in hamsters. In humans, light has been used for treatment of the light-dependent winter depressive disorder. A genetic predisposition for high responsiveness to light may occur in patients with winter depression. The altered gene expression induced by light may account for a unique sensitivity to light and mediate the anti-depressant effect of light treatment.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0785-3890
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
26
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
239-43
|
pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7946241-Circadian Rhythm,
pubmed-meshheading:7946241-Gene Expression Regulation,
pubmed-meshheading:7946241-Geography,
pubmed-meshheading:7946241-Humans,
pubmed-meshheading:7946241-Light,
pubmed-meshheading:7946241-Photoperiod,
pubmed-meshheading:7946241-Phototherapy,
pubmed-meshheading:7946241-Seasonal Affective Disorder
|
pubmed:year |
1994
|
pubmed:articleTitle |
The molecular basis for winter depression.
|
pubmed:affiliation |
Department of Mental Health, National Public Health Institute, Helsinki, Finland.
|
pubmed:publicationType |
Journal Article,
Review
|