Linked Life Data

7945783

Source:http://linkedlifedata.com/resource/pubmed/id/7945783

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1994-12-6
pubmed:abstractText
Achsah Keegan and colleagues consider the signaling mechanisms utilized by the interleukin 4 (IL-4) receptor and review evidence suggesting that these mechanisms can account for the known responses of hematopoietic and non-hematopoietic cells to IL-4. Most of these data have been obtained from analyses of the ability of IL-4 to regulate the growth of IL-3-dependent myeloid cell lines. These results have implicated a pathway of activation homologous to that utilized by insulin and insulin-like growth factor 1 (IGF-1). However, it is possible that the regulation of growth responses through the IL-4 receptor (and other receptors), and the differentiative events elicited in lymphocytes, may not be mediated by the same post-receptor events.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0167-5699
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
423-32
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Interleukin 4 receptor: signaling mechanisms.
pubmed:affiliation
Laboratory of Immunology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892.
pubmed:publicationType
Journal Article, Review