pubmed-article:7945388 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:7945388 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:7945388 | lifeskim:mentions | umls-concept:C0009015 | lld:lifeskim |
pubmed-article:7945388 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:7945388 | lifeskim:mentions | umls-concept:C0215223 | lld:lifeskim |
pubmed-article:7945388 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
pubmed-article:7945388 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
pubmed-article:7945388 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:7945388 | pubmed:dateCreated | 1994-11-23 | lld:pubmed |
pubmed-article:7945388 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7945388 | pubmed:abstractText | A human creatine transporter (hCRT-BS2M) cDNA clone was isolated from a human brainstem/spinal cord using a PCR and phage plaque hybridization based technique. This clone included an open reading frame of 1,905 base pairs(bp) within a 2,283bp cDNA. Northern blot hybridization detected the expression of corresponding mRNAs most prominently in the skeletal muscle, heart and kidney. Peptide sequence analysis of the hCRT-BS2M protein product revealed 12 putative transmembrane domains. The predicted protein sequence further demonstrates that the hCRT-BS2M has highly conserved amino acid identity with the other members of the sodium dependent plasma membrane transporter family. Transient expression of the hCRT-BS2M in COS-7 cells demonstrates sodium dependent [14C]creatine uptake with a KM value of 14.9 +/- 3.0 microM (n = 5) that is attenuated by creatine and selective structural analogues of creatine. | lld:pubmed |
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pubmed-article:7945388 | pubmed:language | eng | lld:pubmed |
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pubmed-article:7945388 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:7945388 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7945388 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:7945388 | pubmed:month | Oct | lld:pubmed |
pubmed-article:7945388 | pubmed:issn | 0006-291X | lld:pubmed |
pubmed-article:7945388 | pubmed:author | pubmed-author:SantoriMM | lld:pubmed |
pubmed-article:7945388 | pubmed:author | pubmed-author:WangYY | lld:pubmed |
pubmed-article:7945388 | pubmed:author | pubmed-author:WeiHH | lld:pubmed |
pubmed-article:7945388 | pubmed:author | pubmed-author:RoeskeW RWR | lld:pubmed |
pubmed-article:7945388 | pubmed:author | pubmed-author:NguyenMM | lld:pubmed |
pubmed-article:7945388 | pubmed:author | pubmed-author:RichmanJJ | lld:pubmed |
pubmed-article:7945388 | pubmed:author | pubmed-author:WaiteSS | lld:pubmed |
pubmed-article:7945388 | pubmed:author | pubmed-author:REGOS FSF | lld:pubmed |
pubmed-article:7945388 | pubmed:author | pubmed-author:HorvathRR | lld:pubmed |
pubmed-article:7945388 | pubmed:author | pubmed-author:VanderahTT | lld:pubmed |
pubmed-article:7945388 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:7945388 | pubmed:day | 14 | lld:pubmed |
pubmed-article:7945388 | pubmed:volume | 204 | lld:pubmed |
pubmed-article:7945388 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:7945388 | pubmed:authorsComplete | N | lld:pubmed |
pubmed-article:7945388 | pubmed:pagination | 419-27 | lld:pubmed |
pubmed-article:7945388 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:7945388 | pubmed:year | 1994 | lld:pubmed |
pubmed-article:7945388 | pubmed:articleTitle | The cloning and expression of a human creatine transporter. | lld:pubmed |
pubmed-article:7945388 | pubmed:affiliation | Department of Pharmacology, College of Medicine, University of Arizona, Tucson 85724. | lld:pubmed |
pubmed-article:7945388 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:7945388 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:7945388 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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