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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1994-11-8
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pubmed:abstractText |
Isoflurane-N2O anesthesia (as compared with halothane-N2O) reduces the cerebral blood flow (CBF) at which electroencephalographic changes occur in humans subjected to carotid occlusion. In contrast, no differences were seen in rats when cortical depolarization (instead of the electroencephalogram) was used as the ischemic marker during equi-MAC isoflurane-N2O and halothane-N2O anesthesia. To extend these findings, we used laser-Doppler flowmetry to continuously examine CBF (CBFLDF) and attempted to better define the relation between CBF and the time to depolarization (as a measure of the rate of energy depletion after ischemia).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0003-3022
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
965-73
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7943848-Anesthesia, Inhalation,
pubmed-meshheading:7943848-Animals,
pubmed-meshheading:7943848-Blood Pressure,
pubmed-meshheading:7943848-Brain,
pubmed-meshheading:7943848-Brain Ischemia,
pubmed-meshheading:7943848-Cerebrovascular Circulation,
pubmed-meshheading:7943848-Drug Interactions,
pubmed-meshheading:7943848-Halothane,
pubmed-meshheading:7943848-Isoflurane,
pubmed-meshheading:7943848-Laser-Doppler Flowmetry,
pubmed-meshheading:7943848-Male,
pubmed-meshheading:7943848-Microelectrodes,
pubmed-meshheading:7943848-Nitrous Oxide,
pubmed-meshheading:7943848-Rats,
pubmed-meshheading:7943848-Rats, Sprague-Dawley,
pubmed-meshheading:7943848-Regional Blood Flow,
pubmed-meshheading:7943848-Time Factors,
pubmed-meshheading:7943848-Tritium
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pubmed:year |
1994
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pubmed:articleTitle |
Ischemic depolarization during halothane-nitrous oxide and isoflurane-nitrous oxide anesthesia. An examination of cerebral blood flow threshold and times to depolarization.
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pubmed:affiliation |
Department of Anesthesia, University of Iowa College of Medicine, Iowa City.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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