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rdf:type |
|
|
lifeskim:mentions |
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|
pubmed:issue |
4
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|
pubmed:dateCreated |
1994-11-8
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|
pubmed:abstractText |
We previously described the use of the nematode Caenorabditis elegans as a genetic model for studying the mechanism of action of volatile anesthetics. All previous strains of C. elegans with altered responses to anesthetics have been identified by screening the response to halothane. The current study was designed to identify classes of mutations by screening for alterations in sensitivity to enflurane, isoflurane, and diethylether.
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pubmed:grant |
|
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pubmed:language |
eng
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|
pubmed:journal |
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|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Oct
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|
pubmed:issn |
0003-3022
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
81
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|
pubmed:geneSymbol |
fc20,
fc21,
fc34,
unc-1,
unc-7,
unc-79,
unc-9
|
|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
888-98
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7943840-Anesthetics,
pubmed-meshheading:7943840-Animals,
pubmed-meshheading:7943840-Caenorhabditis elegans,
pubmed-meshheading:7943840-Chromosome Mapping,
pubmed-meshheading:7943840-Dose-Response Relationship, Drug,
pubmed-meshheading:7943840-Drug Hypersensitivity,
pubmed-meshheading:7943840-Enflurane,
pubmed-meshheading:7943840-Ether, Ethyl,
pubmed-meshheading:7943840-Halothane,
pubmed-meshheading:7943840-Isoflurane,
pubmed-meshheading:7943840-Models, Genetic,
pubmed-meshheading:7943840-Mutation
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|
pubmed:year |
1994
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|
pubmed:articleTitle |
Mutations conferring new patterns of sensitivity to volatile anesthetics in Caenorhabditis elegans.
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|
pubmed:affiliation |
Department of Anesthesiology, University Hospitals of Cleveland, Ohio.
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|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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