Linked Life Data

7939535

Source:http://linkedlifedata.com/resource/pubmed/id/7939535

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
39
pubmed:dateCreated
1994-11-10
pubmed:abstractText
The sensitivity to the major antimicrobial agents of consecutively isolated gram-negative rods in intensive care units in Switzerland was investigated. A majority of strains originated from clinical specimens where infection or colonization could not be distinguished from each other. A total of 1024 isolates from 482 patients were tested by a standardized microtiter method. Of the beta-lactam antibiotics, imipenem (92% of bacteria sensitive), ceftazidime (90%), and aztreonam (85%) showed the greatest activity. 94% of the isolates were sensitive to ciprofloxacin, and 93% and 91% to amikacin and tobramycin respectively. There where considerable differences locally and in time, probably reflecting small outbreaks due to resistant bacteria and because selective pressure is locally dependent on the antimicrobial agents used. 122 patients were observed for an extended period. In 67 (55%) the same gram-negative rods persisted for up to 42 days without development of resistance. In 41 patients (34%) there was a change to other more resistant bacteria, especially to multi-resistant Pseudomonas aeruginosa, Flavobacterium meningo-septicum, Xanthomonas maltophilia or Enterobacter cloacae. In 12 patients (10%) bacteria of the same species with resistance to additional antimicrobial agents were observed.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0036-7672
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
124
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1695-700
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
[Antibiotic sensitivity of gram-negative bacteria in intensive care units in Switzerland].
pubmed:affiliation
Institut für medizinische Mikrobiologie, Universität Zürich.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't