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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1994-10-21
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pubmed:abstractText |
We report the unique occurrence of hyperekplexia and obstructive sleep apnea (OSA) in a 48-year-old male. Polysomnography and multiple sleep latency testing excluded cataplexy, which can be confused with startle attacks. A new imaging finding was a nuclear tomography abnormality in the left frontal lobe. We postulate that this finding may represent a functional cortical lesion of a descending pathway that normally inhibits the startle reflex. Serious complications of pharmacotherapy with clonazepam, the drug of choice for hyperekplexia, can be avoided by first evaluating for OSA.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0161-8105
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
280-3
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pubmed:dateRevised |
2009-1-29
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pubmed:meshHeading |
pubmed-meshheading:7939129-Brain,
pubmed-meshheading:7939129-Carotid Artery, Internal,
pubmed-meshheading:7939129-Clonazepam,
pubmed-meshheading:7939129-Electroencephalography,
pubmed-meshheading:7939129-Evoked Potentials, Somatosensory,
pubmed-meshheading:7939129-Frontal Lobe,
pubmed-meshheading:7939129-Humans,
pubmed-meshheading:7939129-Magnetic Resonance Imaging,
pubmed-meshheading:7939129-Male,
pubmed-meshheading:7939129-Middle Aged,
pubmed-meshheading:7939129-Polysomnography,
pubmed-meshheading:7939129-Protriptyline,
pubmed-meshheading:7939129-Sleep Apnea Syndromes,
pubmed-meshheading:7939129-Sleep Stages,
pubmed-meshheading:7939129-Startle Reaction,
pubmed-meshheading:7939129-Tomography, Emission-Computed, Single-Photon
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pubmed:year |
1994
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pubmed:articleTitle |
Hyperekplexia: report of a nonfamilial adult onset case associated with obstructive sleep apnea and abnormal brain nuclear tomography.
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pubmed:affiliation |
Division of Neurology, Baptist Hospital, Miami, Florida.
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pubmed:publicationType |
Journal Article,
Case Reports
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