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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1994-11-16
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pubmed:abstractText |
From 1985 through 1992 the following hepatitis B markers HBsAg, anti-HBs and anti-HBc were evaluated in 1797 injecting drug users (IDUs) attending 8 Centers for drug addicts in the Veneto region (north-east Italy). Among all IDUs, 1004 (56%) proved to be positive for at least one of the above markers. In particular our aim was to study the carriers of only anti-HBc. At entry, among these 1004 IDUs, 294 (29%) showed only the anti-HBc; 141 IDUs of them have been followed for a period of time: 77% remained without any marker change and 23% showed the appearance of anti-HBs. Subsequently, other 75 IDUs became carrier only of the anti HBc, for the following reasons: loss of anti-HBs (57%) or HBsAg (15%) appearance only of anti-HBc (28%). No carrier of only anti-HBc seroconverted for HBsAg. The evaluation of our data supports the hypothesis that the carrier status of the only anti-HBc prevents from reinfection by HBV and therefore these subjects do not need vaccination.
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pubmed:language |
ita
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0034-1193
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
85
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
419-24
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7938872-Adolescent,
pubmed-meshheading:7938872-Adult,
pubmed-meshheading:7938872-Biological Markers,
pubmed-meshheading:7938872-Carrier State,
pubmed-meshheading:7938872-Female,
pubmed-meshheading:7938872-Hepatitis B,
pubmed-meshheading:7938872-Hepatitis B Antibodies,
pubmed-meshheading:7938872-Hepatitis B Core Antigens,
pubmed-meshheading:7938872-Humans,
pubmed-meshheading:7938872-Italy,
pubmed-meshheading:7938872-Male,
pubmed-meshheading:7938872-Prevalence,
pubmed-meshheading:7938872-Seroepidemiologic Studies,
pubmed-meshheading:7938872-Street Drugs,
pubmed-meshheading:7938872-Substance Abuse, Intravenous
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pubmed:year |
1994
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pubmed:articleTitle |
[The significance of the isolated anti-HBc carrier. A study of 1797 drug addicts. The Intersert Group of Scientific Collaboration].
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pubmed:affiliation |
Istituto di Clinica Medica, Università, Verona.
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pubmed:publicationType |
Journal Article,
English Abstract
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