Linked Life Data

7937334

Source:http://linkedlifedata.com/resource/pubmed/id/7937334

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1994-11-22
pubmed:abstractText
Neuropeptide Y (NPY) was shown to increase feeding when injected into the hypothalamus. Neuropeptide Y antibody (aNPY) decreased feeding in the ventromedial area of the hypothalamus as well as when it was injected into the ventromedial or ventrolateral areas of the thalamus, but not when injected into other hypothalamic areas. The decrease in feeding produced by aNPY in the hypothalamus was associated with a sterotypic increase in general activity in the hypothalamus, circling in the ventromedial thalamic area, and barrel rolling in the ventrolateral thalamic area. Neuropeptide Y antibody also reduced by 54-73% the time it required for mice to recover from anesthesia. The marked increase in stereotypic activity and enhanced recovery from anesthetic suggest that blocking endogenous NPY released the brain areas from inhibitory control. These studies further confirm a physiological role for NPY in the central nervous system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0196-9781
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
607-13
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Effects of localized injections of neuropeptide Y antibody on motor activity and other behaviors.
pubmed:affiliation
VA Medical Center, Geriatric Research Educational and Clinical Center, St. Louis, MO 63109.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't