Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1994-11-2
|
pubmed:abstractText |
Biapenem (L-627) was given intravenously to 17 children with acute bacterial infections including 3 with purulent tonsillitis, 1 with bronchitis, 4 with pneumonia, 2 with sepsis, 3 with pyelonephritis, 2 with SSSS. (2 cases are omitted from evaluation because of Mycoplasma pneumonia and infectious mononucleosis). Daily dosages per kg bodyweight ranging from 18.3 to 60 mg were given in 3 divided doses per day for 4 to 6 days. Clinical responses were excellent in 12 (80%), good in 2 (13.3%), fair in 1 (6.7%) and poor in 0 (0%), with an overall efficacy rate of 93.3%. Good bacteriological responses were obtained in all of the 9 cases from which pathogens were identified. A side effect is observed in only 1 case with mild diarrhea. The above results suggest that L-627 is a useful new carbapenem derivative for the treatment of bacterial infections in children.
|
pubmed:language |
jpn
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0368-2781
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
47
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
882-8
|
pubmed:dateRevised |
2009-11-11
|
pubmed:meshHeading |
pubmed-meshheading:7933522-Bacterial Infections,
pubmed-meshheading:7933522-Child,
pubmed-meshheading:7933522-Child, Preschool,
pubmed-meshheading:7933522-Diarrhea,
pubmed-meshheading:7933522-Female,
pubmed-meshheading:7933522-Humans,
pubmed-meshheading:7933522-Infant,
pubmed-meshheading:7933522-Male,
pubmed-meshheading:7933522-Respiratory Tract Infections,
pubmed-meshheading:7933522-Thienamycins
|
pubmed:year |
1994
|
pubmed:articleTitle |
[Clinical studies on biapenem (L-627) in the pediatric field].
|
pubmed:affiliation |
Department of Pediatrics, Aomori Prefectural Central Hospital.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
English Abstract
|