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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1994-11-22
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pubmed:abstractText |
An enzyme-linked immunoabsorbent spot (ELISPOT) assay has been developed for measuring the frequency of interferon-gamma (IFN-gamma) producing cells in rhesus monkeys. Aged monkeys revealed, upon mitogenic stimulation, a significantly higher percentage of IFN-gamma secreting peripheral blood mononuclear cells (PBMC) compared to young animals. No correlation was found between the frequency of IFN-gamma producing PBMC and the mitogen-driven proliferation, indicating that in rhesus monkeys no direct correlation exists between these two activation parameters.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0047-2565
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
42-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:7932638-Age Factors,
pubmed-meshheading:7932638-Animals,
pubmed-meshheading:7932638-Concanavalin A,
pubmed-meshheading:7932638-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:7932638-Female,
pubmed-meshheading:7932638-Interferon-gamma,
pubmed-meshheading:7932638-Leukocytes, Mononuclear,
pubmed-meshheading:7932638-Lymphocyte Activation,
pubmed-meshheading:7932638-Macaca mulatta,
pubmed-meshheading:7932638-Male,
pubmed-meshheading:7932638-Sex Factors,
pubmed-meshheading:7932638-Statistics, Nonparametric,
pubmed-meshheading:7932638-Stimulation, Chemical
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pubmed:year |
1994
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pubmed:articleTitle |
The mitogen-induced generation of interferon-gamma producing cells in cultures of rhesus monkey peripheral blood mononuclear cells is age-dependent.
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pubmed:affiliation |
Department of Chronic and Infectious Diseases, Institute for Applied Radiobiology and Immunology (ITRI)-TNO, Rijswijk, The Netherlands.
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pubmed:publicationType |
Journal Article
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