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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1994-11-3
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pubmed:abstractText |
Bone changes in sickle cell disease occur due to marrow hyperplasia, tissue ischaemia and infarction due to vaso-occlusion. Between 1982 and 1991 thirty four patients were treated in the Orthopaedic and Neurosurgery Departments of the Kind Fahd University Hospital, Al-Khobar, with spinal complications due to sickle cell disease. There were 21 males and 13 females aged between 4 and 28 years (mean 17.4 years). Structural changes in the vertebral bodies due to marrow hyperplasia occurred in 44% of the patients. Avascular necrosis leading to collapse of the vertebral bodies was seen in 9 (27%) patients. Infective spondylitis was the most serious complication seen in 8 (24%) patients; the majority needed anterolateral decompression and bone grafting. The spine is often affected in sickle cell disease and aggressive treatment with close follow-up is required to avoid disabling complications.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0341-2695
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
154-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7927964-Adolescent,
pubmed-meshheading:7927964-Adult,
pubmed-meshheading:7927964-Anemia, Sickle Cell,
pubmed-meshheading:7927964-Bacterial Infections,
pubmed-meshheading:7927964-Child,
pubmed-meshheading:7927964-Child, Preschool,
pubmed-meshheading:7927964-Female,
pubmed-meshheading:7927964-Humans,
pubmed-meshheading:7927964-Lumbar Vertebrae,
pubmed-meshheading:7927964-Male,
pubmed-meshheading:7927964-Middle Aged,
pubmed-meshheading:7927964-Osteonecrosis,
pubmed-meshheading:7927964-Spinal Diseases,
pubmed-meshheading:7927964-Spondylitis
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pubmed:year |
1994
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pubmed:articleTitle |
The spine in sickle cell disease.
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pubmed:affiliation |
Department of Orthopaedic Surgery, College of Medicine and Medical Sciences, King Faisal University, Dammam, Saudi Arabia.
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pubmed:publicationType |
Journal Article
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