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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
1994-11-4
|
| pubmed:abstractText |
The feasibility of transcatheter laser coagulation of atrial myocardium was tested in a canine model by using a combined electrode-laser catheter. In 17 anaesthetized beagles a total of 264 lesions, 12-19 per dog, and 3-5 in each area were produced in: (1) the lateral walls, (2) the posterior right atrial walls, (3) the inter-atrial septum, and (4) the atrial appendage. The power source was a continuous wave Nd:YAG laser. Irradiance was 1 kW.cm-2, at a wave length of 1064 nm, the irradiated spot diameter was 2.0-2.5 mm, and the pulse duration 5-60 s. Local intra-cardiac atrial potentials recorded from the targeted areas during laser irradiation dwindled after onset of the laser pulse, and their amplitude was reduced persistently by pulses of 15 s or longer. Histopathologically, the acute lesions showed intramural haemorrhage and coagulation necrosis, but there was no tissue vaporization or crater formation. Chronic lesions showed clear-cut oval-shaped areas of transmural fibrosis. Diameters of lesions, dependent on the amount of laser energy applied, measured from 4.6 +/- 0.5 mm (450 J) to 7.8 +/- 1.4 mm (1800 J). Follow-up lasted 6-25 months (average 10.5). All the animals survived the procedure without complications. Transcatheter laser coagulation of atrial myocardium is safe and can be performed in a controllable manner by using the catheter system presented.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0195-668X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
971-80
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:7925520-Action Potentials,
pubmed-meshheading:7925520-Animals,
pubmed-meshheading:7925520-Atrial Function,
pubmed-meshheading:7925520-Catheter Ablation,
pubmed-meshheading:7925520-Dogs,
pubmed-meshheading:7925520-Electrocardiography,
pubmed-meshheading:7925520-Feasibility Studies,
pubmed-meshheading:7925520-Female,
pubmed-meshheading:7925520-Follow-Up Studies,
pubmed-meshheading:7925520-Heart Atria,
pubmed-meshheading:7925520-Laser Coagulation,
pubmed-meshheading:7925520-Male,
pubmed-meshheading:7925520-Monitoring, Intraoperative,
pubmed-meshheading:7925520-Time Factors
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Catheter-directed laser coagulation of atrial myocardium in dogs.
|
| pubmed:affiliation |
1. Medical Department, Harlaching Hospital, Munich, Germany.
|
| pubmed:publicationType |
Journal Article
|