Linked Life Data

792420

Source:http://linkedlifedata.com/resource/pubmed/id/792420

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1977-1-29
pubmed:abstractText
1. Insulin secretion of individual isolated islets of Langerhans from mice, determined at 15 second intervals, demonstrated a pulsatile pattern. Glucose stimulated increased amounts of insulin to be released from these individual islets. 2. Insulin secretion of individual isolated mouse islets of Langerhans incubated for 5-15 minute intervals showed a direct relationship to concentration. There was negligible "leakage" in the absence of glucose. 3. Serial determination of insulin release from individual islets at 15 sec. intervals also demonstrated augmented magnitude of insulin release in response to increase of glucose in the medium. More important, a pulsatile pattern of insulin release was evident, which may be related to inherent physiological periodicity of islet physiology as also reflected in the pattern of islet electrical activity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0021-7948
pubmed:author
pubmed:issnType
Print
pubmed:volume
72
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
721-8
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Insulin from individual isolated islets of Langerhans 2. Effect of glucose in varying concentrations.
pubmed:publicationType
Journal Article