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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1994-10-28
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pubmed:abstractText |
In summary, much still needs to be learned about the pathogenetic significance of changes in virus load and importantly, the clinical significance of therapy-induced changes in virus load. The failure of current therapeutic regimens to effect a substantive and durable change in virus load is not a failure of the virologic markers per se but is a call for better antiretroviral and immunotherapeutic-based approaches to treat infected patients. At the same time, the experimental therapeutic regimens should be used to elucidate the unresolved pathogenetic nuances of HIV-1 burden that are a necessary prerequisite for developing a more effective containment of replicating HIV-1 and prolonging the lives of our HIV-1-infected patients.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0272-2712
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
14
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
301-11
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:7924193-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:7924193-Antiviral Agents,
pubmed-meshheading:7924193-Clinical Trials as Topic,
pubmed-meshheading:7924193-DNA, Viral,
pubmed-meshheading:7924193-HIV-1,
pubmed-meshheading:7924193-Humans,
pubmed-meshheading:7924193-Research Design,
pubmed-meshheading:7924193-Virus Replication
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pubmed:year |
1994
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pubmed:articleTitle |
HIV-1 burden as a marker of disease progression and clinical response to therapy in AIDS.
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pubmed:affiliation |
Department of Laboratory Medicine, University of Washington, Seattle.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review
|