Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1994-10-28
pubmed:abstractText
In summary, much still needs to be learned about the pathogenetic significance of changes in virus load and importantly, the clinical significance of therapy-induced changes in virus load. The failure of current therapeutic regimens to effect a substantive and durable change in virus load is not a failure of the virologic markers per se but is a call for better antiretroviral and immunotherapeutic-based approaches to treat infected patients. At the same time, the experimental therapeutic regimens should be used to elucidate the unresolved pathogenetic nuances of HIV-1 burden that are a necessary prerequisite for developing a more effective containment of replicating HIV-1 and prolonging the lives of our HIV-1-infected patients.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0272-2712
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
301-11
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
HIV-1 burden as a marker of disease progression and clinical response to therapy in AIDS.
pubmed:affiliation
Department of Laboratory Medicine, University of Washington, Seattle.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review