Linked Life Data

7922432

Source:http://linkedlifedata.com/resource/pubmed/id/7922432

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-11-8
pubmed:abstractText
Neuromuscular blocking agents (NMBAs) are used in critical illness to reduce metabolic demands and prevent ventilator asynchrony in patients refractory to sedation and anxiolysis. Concurrent interventions for patients receiving neuromuscular blockade include many factors related to prevention, maintenance, and monitoring during immobilization. Prevention interventions include skin care, turning regimes, physical therapy, eye care, and pulmonary toilet to prevent atelectasis, pneumonia, skin breakdown, and corneal ulceration. Maintenance interventions include provision of nutrition, sedation, anxiolysis, and psychosocial support. Monitoring interventions include trending oxygenation parameters and ventilatory care parameters, as well as assessment of the depth of paralysis by assessing clinical evidence of movement, airway pressure waveforms, and peripheral nerve stimulation results. Cost of therapy is influenced by preventing the side-effects of immobility, the choice of NMBA, and concurrent drug therapies, as well as by titration of the NMBA to the lowest drug dose possible to obtain clinical end-points. Clinical end-points are individualized by the prescribing physician and may range from "no movement" to "movement acceptable but no evidence of spontaneous respirations" to "movement acceptable but no ventilator asynchrony." Whenever "no movement"c is identified as the goal, a nerve stimulator is used to identify the depth of paralysis and prevent accidental surplus drug administration, which may result in prolonged paralysis. Methods for using the nerve stimulator and troubleshooting techniques are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1063-7389
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
75-84
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Neuromuscular blockade: indications, peripheral nerve stimulation, and other concurrent interventions.
pubmed:affiliation
University of California Medical Center, San Diego 92103.
pubmed:publicationType
Journal Article, Review