Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1994-10-21
pubmed:abstractText
Dispersions of the diacetylenic phosphatidylcholine, 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine, DC8,9PC, undergo a change from vesicles to hollow tubes on cooling. We report here a light scattering and multinuclear NMR study of the lipid vesicles over the temperature range 0-50 degrees C. The 'splitting' of the N+(CH3)3 resonance increases with decreasing temperature, consistent with the light scattering measurements which show a decrease in vesicle size with decreasing temperature. The NMR spectrum remains well-resolved over this temperature range, even at temperatures as low as 3 degrees C. Phosphorus NMR also indicates that the 'bilayer structure' is maintained over this temperature range. The various proton resonances and the phosphorous signal from the lipid vesicles broaden as the temperature is lowered. These results will be helpful in developing a model for the tubule-forming ability of DC8,9PC.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0006-3002
pubmed:author
pubmed:issnType
Print
pubmed:day
14
pubmed:volume
1194
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
233-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
A temperature study of diacetylenic phosphatidylcholine vesicles.
pubmed:affiliation
Department of Radiation Oncology, East Carolina University School of Medicine, Greenville, NC 27858.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't