Linked Life Data

791749

Source:http://linkedlifedata.com/resource/pubmed/id/791749

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1977-1-25
pubmed:abstractText
Depilated is a recessive mutation on Chromosome 4 in the position b-1.93+/-0.51-dep-3.45+/-0.68.-Pt. It causes severe abnormalities of hair structure. The site of action of dep was investigated by the method of dermal-epidermal recombination. Skins from 14-day mutant and normal mouse embryos were separated into dermal and epidermal components, recombined, and grown in histocompatible mouse testes for 20 days. The recombinations made were +/+ epidermis with +/+ dermis, +/+ epidermis with dep/dep dermis, dep/dep epidermis with +/+ dermis and dep/dep epidermis with dep/dep dermis. Grafts that contained mutant epidermis as one of the components produced hairs that were similar to those found in depilated mice. There was no observable effect of the dermis on hair types produced in this experiment.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0016-6731
pubmed:author
pubmed:issnType
Print
pubmed:volume
84
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
59-65
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Depilated (dep), a mutant gene that affects the coat of the mouse and acts in the epidermis.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.